Pirana 모델링 워크벤치
Pirana PMX Modeling Software
Premier Workbench for Pharmacometric Workflows
Unify PMX workflows for faster, and more reliable drug development
Since its inception, pharmacometrics (PMX) has required solving unique problems without predefined solutions, leading to a diverse set of skills and tools used in PMX workflows. As model-informed drug development (MIDD) gains wider acceptance, the ability to harmonize work across various tools will be critical to ensuring quality, efficiency, and impact on development programs.
Pirana is a comprehensive PMX Modeling Software that integrates these tools into a unified user experience. By providing modelers with a structured framework, Pirana accelerates the iterative process of PMX model development and evaluation, leading to more organized, efficient, and insightful analysis of pharmacometric data. The result? Better informed decisions and higher quality submissions sooner.
How pharmacometricians benefit from Pirana Modeling Workbench
1.
Streamline workflow and tool integration
2.
Full model diagnostics and evaluation
3.
Machine Learning-Based Model Selection (genetic algorithm, random forest, and more)
4.
Fully customizable via close integration with R
Optimize Pharmacometrics’ Workflows with Pirana
Deliver faster, more efficient modeling and simulation by connecting multiple tools for optimizing a pharmacometrics workflow. A graphical user interface provides an automated folder structure for the storage of analytical results, adding order and traceability to complex analyses. Pirana integrates seamlessly with R Speaks NLME, NONMEM, R, and Perl Speaks NONMEM (PSN) and is supported on both Windows and Linux operating systems.
One Tool to Build Better popPK Models
- Organizing and Managing Models – Pirana provides a digital lab notebook-like structure to manage and track PMX data, creating order with automated folder structures for efficient workflows.
- Analyzing Data and Generating Reports – Pirana’s interface supports easy R plotting and reporting in various formats, with the “Model Results” Shiny app enabling custom visual outputs and reproducible R markdown files.
- Visualizing Model Selection and Diagnostics – Pirana’s Visual Run Record captures model selection steps, supporting quick diagnostics and comparisons with interactive summaries for clearer decision-making.
Machine Learning Based Automated Model Selection
The Darwin Model Search feature in Pirana provides a streamlined user interface to pyDarwin, a cutting edge open-source Python package funded by the US FDA that implements several machine learning algorithms for automated pharmacometrics (PMX) model selection. Darwin 검색을 통해 선택한 최적의 모델은 PMX 워크플로 관리에 사용하는 기존 Pirana 도구 제품군과 완벽하게 호환됩니다.
Key Features of Pirana PMX Modeling Software
Model Templates & Wizards
Ready-to-use templates and wizards simplify model creation and execution.
Goodness-of-Fit Plots
Built-in R tools for generating plots that support thorough model evaluation.
Seamless Tool Integration
Connects with R, RsNLME, NONMEM, pyDarwin, and Simcyp for efficient model execution.
ML-Based Model Selection
Uses pyDarwin’s machine learning for automated, optimal model selection.
Comprehensive Reporting
Generates detailed reports in formats like Word, LaTeX, HTML, and PDF with R-based visualization.
Automated Folder Structure
Organizes results for easy traceability and management.
Cross-Platform Compatibility
Supported on Windows, CentOS/RHEL, and Ubuntu.
Visual Run Record
Interactive visualization to document model development and evaluations.
New in Pirana 24.9.1
- Simcyp Integration: Supports virtual bioequivalence for long-acting injectables via Simcyp V23.
- Enhanced Script Library: New scripts improve post-processing and model evaluation.
- Simplified License Management: Integrated with Certara Admin for easy license management.
Schedule a live demo of Pirana PMX Modeling Software, or request a free trial
Complete the form to book your no-obligation demo or try Pirana PMX Modeling Software for free!